Robert B Zurier, Sumner H Burstein Cannabinoids apparently act on inflammation through mechanisms different from those of agents such as nonsteroidal anti-inflammatory drugs (NSAIDs). As a class, the cannabinoids are generally free from the adverse effects associated with NSAIDs. Their clinical development thus provides a new approach to treatment of diseases characterized by acute and chronic inflammation and fibrosis. A concise survey of the anti-inflammatory actions of the phytocannabinoids Δ(9)-tetrahydrocannabinol (THC), cannabidiol, cannabichromene, and cannabinol is presented... Click Below for [...]
HealthMax Cannabinoid Ailment Chart Some cannabinoids bind more selectively to certain receptors and are more specific for desired medicinal usage. Use our Cannabinoid Ailment Chart to find blends which are best suited to your needs.
Bo Liu, Shuang Song, Inmaculada Ruz Maldonado, Attilio Pingitore, Guo C Huang, David Baker, Peter M Jones, Shanta J Persaud AIMS: The novel cannabinoid receptor GPR55 is expressed by rodent islets and it has been implicated in β-cell function in response to a range of ligands. This study evaluated the effects of GPR55 ligands on intracellular calcium ([Ca(2+) ]i ) levels and insulin secretion from islets isolated from GPR55 knockout (GPR55(-/-) ) mice, age-matched wildtype (WT) mice, and human pancreas. [...]